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Table 6 Enriched terms in the profiling analysis of no-SCD patients, not identified in the SCD patients

From: Enrichment analysis applied to disease prognosis

Acc Name p-value p-Bonf SFreq PFreq
  Biological process    
GO:0001980 Regulation of systemic arterial blood 6.0E-41 4.4E-39 13% 0.00
  pressure by ischemic conditions     
GO:0001976 Neurological system process involved in regulation 3.4E-25 2.5E-23 13% 0.00
  of systemic arterial blood pressure     
GO:0006940 Regulation of smooth muscle contraction 6.6E-19 4.9E-17 13% 0.00
GO:0007522 Visceral muscle development 5.3E-03 3.9E-01 1% 0.00
GO:0042694 Muscle cell fate specification 5.3E-03 3.9E-01 1% 0.00
GO:0055009 Atrial cardiac muscle tissue morphogenesis 2.6E-02 1.9E+00 1% 0.00
GO:0003228 Atrial cardiac muscle tissue development 2.6E-02 1.9E+00 1% 0.00
GO:0048739 Cardiac muscle fiber development 4.2E-02 3.1E+00 1% 0.00
GO:0042693 Muscle cell fate commitment 5.7E-02 4.2E+00 1% 0.00
  Molecular function    
GO:0031014 Troponin T binding 9.9E-33 7.3E-31 13% 0.00
GO:0019855 Calcium channel inhibitor activity 1.9E-31 1.4E-29 13% 0.00
GO:0008200 Ion channel inhibitor activity 1.4E-23 1.0E-21 13% 0.00
GO:0016248 Channel inhibitor activity 1.4E-23 1.0E-21 13% 0.00
GO:0005246 Calcium channel regulator activity 4.9E-23 3.6E-21 13% 0.00
GO:0048306 Calcium-dependent protein binding 1.1E-19 8.1E-18 13% 0.00
GO:0042805 Actinin binding 5.6E-06 4.2E-04 4% 0.00
GO:0030899 Calcium-dependent ATPase activity 1.6E-02 1 1% 0.00
GO:0003785 Actin monomer binding 7.2E-02 1 1% 0.00
  1. The terms shown are the biological process and molecular function terms identified as enriched in the profiling analysis of no-SCD patients that were not identified in the profiling of SCD patients. For each term is indicated: GO accession number (Acc), term name, p-value without multiple-testing correction, p-value with Bonferroni correction (p-Bonf), annotation frequency in the study set (SFreq) and annotation frequency in the population set (PFreq).