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|
Acc
|
Name
|
p-value
|
p-Bonf
|
SFreq
|
PFreq
|
|---|
| |
Biological process
| | | |
|---|
|
GO:0001980
|
Regulation of systemic arterial blood
|
6.0E-41
|
4.4E-39
|
13%
|
0.00
|
| |
pressure by ischemic conditions
| | | | |
|
GO:0001976
|
Neurological system process involved in regulation
|
3.4E-25
|
2.5E-23
|
13%
|
0.00
|
| |
of systemic arterial blood pressure
| | | | |
|
GO:0006940
|
Regulation of smooth muscle contraction
|
6.6E-19
|
4.9E-17
|
13%
|
0.00
|
|
GO:0007522
|
Visceral muscle development
|
5.3E-03
|
3.9E-01
|
1%
|
0.00
|
|
GO:0042694
|
Muscle cell fate specification
|
5.3E-03
|
3.9E-01
|
1%
|
0.00
|
|
GO:0055009
|
Atrial cardiac muscle tissue morphogenesis
|
2.6E-02
|
1.9E+00
|
1%
|
0.00
|
|
GO:0003228
|
Atrial cardiac muscle tissue development
|
2.6E-02
|
1.9E+00
|
1%
|
0.00
|
|
GO:0048739
|
Cardiac muscle fiber development
|
4.2E-02
|
3.1E+00
|
1%
|
0.00
|
|
GO:0042693
|
Muscle cell fate commitment
|
5.7E-02
|
4.2E+00
|
1%
|
0.00
|
| |
Molecular function
| | | |
|
GO:0031014
|
Troponin T binding
|
9.9E-33
|
7.3E-31
|
13%
|
0.00
|
|
GO:0019855
|
Calcium channel inhibitor activity
|
1.9E-31
|
1.4E-29
|
13%
|
0.00
|
|
GO:0008200
|
Ion channel inhibitor activity
|
1.4E-23
|
1.0E-21
|
13%
|
0.00
|
|
GO:0016248
|
Channel inhibitor activity
|
1.4E-23
|
1.0E-21
|
13%
|
0.00
|
|
GO:0005246
|
Calcium channel regulator activity
|
4.9E-23
|
3.6E-21
|
13%
|
0.00
|
|
GO:0048306
|
Calcium-dependent protein binding
|
1.1E-19
|
8.1E-18
|
13%
|
0.00
|
|
GO:0042805
|
Actinin binding
|
5.6E-06
|
4.2E-04
|
4%
|
0.00
|
|
GO:0030899
|
Calcium-dependent ATPase activity
|
1.6E-02
|
1
|
1%
|
0.00
|
|
GO:0003785
|
Actin monomer binding
|
7.2E-02
|
1
|
1%
|
0.00
|
- The terms shown are the biological process and molecular function terms identified as enriched in the profiling analysis of no-SCD patients that were not identified in the profiling of SCD patients. For each term is indicated: GO accession number (Acc), term name, p-value without multiple-testing correction, p-value with Bonferroni correction (p-Bonf), annotation frequency in the study set (SFreq) and annotation frequency in the population set (PFreq).