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Table 5 Top 10 enriched cellular component terms in the profiling analysis of SCD patients

From: Enrichment analysis applied to disease prognosis

Acc Name p-value p-Bonf SFreq PFreq
GO:0005859 Muscle myosin complex 2.4E-37 1.3E-35 81% 0.10%
GO:0032982 Myosin filament 2.4E-37 1.3E-35 81% 0.10%
GO:0016460 Myosin II complex 1.1E-35 5.8E-34 81% 0.13%
GO:0001725 Stress fiber 4.1E-20 2.2E-18 56% 0.25%
GO:0032432 Actin filament bundle 7.3E-20 3.8E-18 56% 0.27%
GO:0014705 C zone 9.2E-15 4.9E-13 25% 0.01%
GO:0005863 Striated muscle myosin thick filament 1.0E-12 5.4E-11 25% 0.02%
GO:0031672 A band 4.7E-09 2.5E-07 25% 0.13%
GO:0005861 Troponin complex 2.2E-05 1.1E-03 13% 0.04%
GO:0005865 Striated muscle thin filament 6.6E-05 3.5E-03 13% 0.07%
  1. The terms shown are the 10 cellular component terms with the lowest p-value, obtained in the profiling of SCD patients. For each term is indicated: GO accession number (Acc), term name, p-value without multiple-testing correction, p-value with Bonferroni correction (p-Bonf), annotation frequency in the study set (SFreq) and annotation frequency in the population set (PFreq).